PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells

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PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells

The double-stranded RNA-activated protein kinase R (PKR) is a Type I interferon (IFN) stimulated gene that has important biological and immunological functions. In viral infections, in general, PKR inhibits or promotes viral replication, but PKR-IPNV interaction has not been previously studied. We investigated the involvement of PKR during infectious pancreatic necrosis virus (IPNV) infection u...

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Homologous viral interference in trout and Atlantic salmon cell cultures infected with infectious pancreatic necrosis virus.

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ژورنال

عنوان ژورنال: Viruses

سال: 2016

ISSN: 1999-4915

DOI: 10.3390/v8060173